Transbuccal delivery of 5-Aza-2′-deoxycytidine: Effects of drug concentration, buffer solution, and bile salts on permeation
نویسندگان
چکیده
منابع مشابه
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
The major goal of epigenetic therapy is to reverse aberrant promoter hypermethylation and restore normal function of tumor suppressor genes by the use of chromatin-modifying drugs. Decitabine, or 5-aza-2'-deoxycytidine (5-aza-CdR), is a well-characterized drug that is now Food and Drug Administration approved for the treatment of myelodysplastic syndrome. Although 5-aza-CdR is an extremely pote...
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the effects of previewing and providing background knowledge on iranian university efl learners’ comprehension of literary and academic texts
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2007
ISSN: 1530-9932
DOI: 10.1208/pt0803055